

World AIDS Day is held on the 1st December each year and is an opportunity for people worldwide to unite in the fight against HIV, show their support for people living with HIV and to commemorate people who have died. World AIDS Day was the first ever global health day, held for the first time in 1988. Over 100,000 people are living with HIV in the UK. Globally there are an estimated 34 million people who have the virus. Despite the virus only being identified in 1984, more than 35 million people have died of HIV or AIDS, making it one of the most destructive pandemics in history. World AIDS Day is important because it reminds the public and Government that HIV has not gone away there is still a vital need to raise money, increase awareness, fight prejudice and improve education.
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- 02 Oct – Annie Leibovitz (1949–), American portrait photographer
- 03 Oct – Eleonora Duse (1858–1924), Italian actress
- 04 Oct – Jóhanna Sigurðardóttir (1942–), Icelandic politician, former Prime Minister of Iceland, world's first openly gay head of government
- 08 Oct – Kristanna Loken (1979–), American model & actress
- 11 Oct – Eleanor Roosevelt (1884–1962), former First Lady of the USA & human rights activist
- 15 Oct – Jenna Talackova, Canadian beauty pageant contestant, model & TV personality
- 17 Oct – Laura Nyro (1947–1997), American songwriter, singer & pianist
- 18 Oct – Brittney Griner (1990–), American basketball player
- 18 Oct – Martina Navratilova (1956–), American tennis player
- 22 Oct – Saffron Burrows (1972–), English actress
- 23 Oct – Jean Acker (1893–1978), American actress
- 23 Oct – Ireland Baldwin (1995–), American model
- 23 Oct – Lilyan Tashman (1896–1934), American actress
- 25 Oct – Chely Wright (1970–), American country singer-songwriter
- 25 Oct – Claude Cahun (1894–1954), French artist, photographer & writer
- 26 Oct – Liliane Maestrini (1987–), Brazilian beach volleyball player
- 27 Oct – Katherine Bradley (1846–1914), English poet
- 28 Oct – Caitlyn Jenner (1949–), American TV personality & Olympic Gold Medalist in Decathlon (1976)
- 29 Oct – Michelle Brooke-Marciniak (1973–), American business executive, former WNBA basketball player
- 29 Oct – Ann-Marie MacDonald (1958–), Canadian playwright, novelist, actress & broadcast journalist
- 31 Oct – Natalie Clifford Barney (1876–1972), American playwright, poet and novelist